Neuroendocrine cancer blurred vision.

General Endocrinology

Chordomas are slow growing neoplasms arising from notochordal remnants of the axial skeleton. The second most common site for chordomas, after the sacrococcygeal region, is the base of the skull. Skull base chordomas commonly result in cranial nerve deficits, such as blurred vision, facial weakness and swallowing difficulty.

Occasionally, chordomas localized in the hypothalamic or pituitary region may lead to pituitary stalk disjunction, pituitary insufficiency and diabetes insipidus.


Studies show that early diagnosis, combined with aggressive surgical resection, offers the best chance for long-term survival. Although optimal treatment consists of wide excision with adjuvant radiotherapy, skull base chordomas are rarely amenable to complete surgical removal. Traditionally, postoperative irradiation is delivered to doses of cGy; however neuroendocrine cancer blurred vision approach controls the chordoma only for a few years.

Neuroendocrine cancer blurred vision depends on the histological grade of the tumor, atypical chordomas showing the lowest survival rate. Skull base chordomas: a review of 38 patients, Br J Neurosurg ; 7 3 Intracranial chordomas.

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Neuroradiology ; 8 2 Chordoma presenting as pseudoprolactinoma. Br J Neurosurg ; 17 3 Chordoma in the sella turcica. Neurol Med Chir Tokyo ; 42 7 Intrasellar chordomas mimicking pituitary adenoma. J Neurosurg ; 92 6 Hemorrhagic chondroid chordoma mimicking pituitary apoplexy. Neuroradiology ; 40 11 Kikuchi K, Watanabe K.

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Huge sellar chordoma: CT demonstration. Comput Med Imaging Graph ; 18 5 Intracranial chordoma. Case report of a destructively growing chondroid chordoma in the area of the sella turcica.

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Zentralbl Neurochir ; 54 3 A case of sellar chordoma mimicking a non-functioning pituitary adenoma with survival of more than 10 years. Noshuyo Byori ; 10 2 Intrasellar chordoma. Sem Hop ; 56 MR imaging of the sellar and juxtasellar regions.

Radiographics ; 11 5 Infrasellar craniopharyngioma mimicking a clival chordoma: a neuroendocrine cancer blurred vision report. Neurol India ; 50 2 A case of suprasellar intradural chordoma. No Shinkei Geka ; 22 3 Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: surgical experience in cases.

Neurosurge [CrossRef] Extended transsphenoidal approach to giant tumors in sellar and clival area.

neuroendocrine cancer blurred vision

Zhonghua Yi Xue Za Zhi ; 84 20 Clinical application of minimally invasive neuroendoscopic techniques. Radiosurgery for cranial base chordomas and chondrosarcomas. Neurosurgery ; 56 4 [CrossRef] New developments in the pathology of skull base tumors.

neuroendocrine cancer blurred vision

Virchows Arch ; 4 Review of current protocols for protontherapy in USA. Tumori ; 84 Stereotactically delivered cranial radiation therapy: a ten-year experience of linac-based radiosurgery in the UK. Clin Oncol R Coll Radiol ; 11 5

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