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Moldovan Andreea - Centrul de Diagnostic si Tratament Oncologic Human papillomavirus infection poster Citate duplicat In hpv cancer prevention poster to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and neck, causing alterations in DNA.

It has been hpv cancer prevention poster that the human papil­loma­virus HPV type 16, a subtype of the human pa­pil­loma­virus, is present in the oropharyngeal carcinomas of non-smokers patients inclusive.

HPV-infected cells express some viral proteins encoded by genes called E6 and E7, and can inactivate p53 protein and the retinoblastoma-type pro­tein RBP involved in the regulation of proliferation and cell death.

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Materials hpv cancer prevention poster method. We present an immunohistochemical study conducted to identify significant tumour markers in tonsillar SCC. We present the sta­tis­tically human papillomavirus infection poster correlations between the presence of immunohistochemical markers and studied local re­cur­rence, lymph human papillomavirus infection poster recurrence and risk of a second can­cer in the aerodigestive upper tract.

The de­mon­stration of HPV in tonsillar tumour tissue requires in situ hybridization or polymerase chain reaction PCR for the evidence of viral genome included into the host cell. The practical implications of an etiologic role of HPV in head and neck cancer generally and in tonsillar SCC in particular remains in question and is in relate with prog­nosis, treatment and prevention.

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În afară de consumul de tutun şi abuzul de al­cool, anumite virusuri au fost asociate cu carcinomul cu celule scuamoase CCS al capului şi gâtului, cauzând al­te­rări la nivelul ADN-ului. Este dovedit că virusul papiloma uman HPVtipul 16, este prezent la nivelul carcinoamelor orofaringiene inclusiv în cazul nefumătorilor. Celulele in­fec­ta­te cu HPV exprimă unele proteine virale codate de ge­ne­le denumite E6 şi E7 şi pot inactiva proteina p53 şi pro­tei­na de tip retinoblastom RBP implicate în reglarea pro­li­fe­ră­rii şi morţii celulare.

Materiale şi metodă. Pre­zen­tăm un stu­diu imunohistochimic realizat cu scopul de a identifica mar­keri tumorali semnificativi în CCS de amig­da­lă.

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Pre­zen­tăm co­re­la­ţiile semnificative statistic între prezenţa mar­ke­rilor imu­no­his­to­chimici şi recurenţa locală, recurenţa no­du­lilor limfatici şi ris­cul apariţiei unui al doilea cancer în trac­tul aerodigestiv su­pe­rior.

Punerea în evidenţă a HPV-ului în ţesutul tu­mo­ral amigdalian necesită hibridizare in situ şi reacţie de polimerizare în lanţ PCR pentru punerea în hpv cancer prevention poster a genomului viral conţinut în celula-gazdă. Im­pli­caţiile practice ale unui rol etiologic al HPV-ului în can­ce­rele de cap şi gât, în general, şi în CCS human papillomavirus hpv cancer prevention poster poster amigdală, în par­ti­cu­lar, reprezintă un subiect în dezbatere, fiind în relaţie cu prog­nos­ticul, tratamentul şi prevenţia acestor tipuri de can­cere.

Cuvinte cheie carcinomul cu celule scuamoase de amigdală CCS HPV markeri tumorali Introduction The tonsillar squamous cell carcinoma SCC is becoming a public health problem because of its rising incidence in the last 20 years, in contrast to the decreasing incidence of carcinomas in other subsites of head and neck associated to human papillomavirus infection poster reduced prevalence of smoking.

Article Download These tumours of oral cavity, oropha­rynx, larynx, hypopharynx and sinonasal region are linked by common characteristics, including a male predominant appearance in the 5th-6th decade of life, an important etiological link with tobacco, alcohol use or betel hpv cancer prevention poster chewing, and a histopathological resemblance 1.

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Data regarding the epidemiology revealed that in Romania the oropharyngeal cancer represents 2. Experiență profesională: absolvirea Liceului Sanitar Tg. Cancer mamar metastaze Peritoneal cancer loss of appetite In France, during the paraziti mimosa pudica pudra 30 years, the hpv cancer prevention poster in oral and human papillomavirus infection poster cancer increased by three times 1.

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Human papillomavirus infection poster in cervical cancers, the oropharyngeal infection with HPV is a sexually transmitted disease which involves some particularities of sexual behaviour: a large number of vaginal sex partners, oral and anal sex. The recent increasing of OPSCC incidence may reflect the social changes regarding sexual behaviour in the modern world 6.

The anatomical sites preferred by HPV in oropharynx are human papillomavirus infection poster tonsils and the tongue, because of the unique presence of transitional mucosa in oropharynx and particular in tonsillar tissue, which presents important histological similarities with the cervical mucosa.

Tonsillar epithelium invagination may favour virus capture and promote its access to basal cells the only dividing cells in the epithelium. Hpv virus zwanger Dr.

We had human papillomavirus infection poster premises for our study on tonsillar cancers. The second consists in the fact that mutagens such as tobacco, alcohol and HPV viral oncogenes E6 and E7 induce dysfunctions of two major mechanisms of cellular cycle, which involves the p53 and RBP tumoral suppressor genes 2. Materials and method We made an immunohistochemical retrospective study between andaiming to identify any correlations between tumoral markers and the evolution and human papillomavirus infection poster in tonsillar SCC.

Materials We studied 52 cases of patients diagnosed with tonsillar SCC. We had a first group Group I with 25 cases, where the positive hpv cancer prevention poster was made by biopsy and these human papillomavirus infection poster had radiotherapy as first curative method of treatment.

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We had a second group Group II with 27 cases, where the positive human papillomavirus infection poster was made on surgical specimens and these patients had human papillomavirus infection poster as the first curative method of treatment. The two groups were similar regarding age and gender distribution.

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The dilutions and markers specifications are revealed in Table 1. We also studied lymphocyte populations CD4, Hpv cancer prevention poster, and populations of dendritic cells in tumour tissue. Table 1.

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Referințe bibliografice pe an The dilutions and markers specifications For the immunohistochemical human papillomavirus infection poster of tumoral antigens we used the three-stadial indirect method Avidine-Biotine-Peroxidase ABPafter Hsu and colab.

Results The gender repartition of cases was: 47 male cases and 5 female cases.

Human papillomavirus infection poster

The age repartition of cases was: two cases between years old, 14 cases between years old, 21 cases between years old, 10 cases between years old, and five cases between years old.

The correlation coefficient between the two sets of data, corresponding to Group I and Group II, was 0. In both groups, we had 48 smoker patients, representing The patients who were both smokers hpv cancer prevention poster alcohol consumers represented We studied the tumoral markers human papillomavirus infection poster 52 cases of squamous cell carcinoma.

  • In addition to tobacco and alcohol abuse, certain viruses have been associated with squamous cell carcinoma SCC of the head and human papillomavirus infection poster, causing alterations in DNA.
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  • Activitate stiintifica - Human papillomavirus infection poster

We present the results, that we considered immunohistochemically valid and statistically significant Table 2. Table human papillomavirus infection poster. The distribution of tumoral markers in specimens of SCC studied We realised a correlation between the presence of the tumoral marker of a certain type positive and slowly positive results and the post-therapeutic evolution — local recurrence, nodal relapse, the occurrence of second cancers in upper aerodigestive upper ways and distance metastases.

Prevenţia cancerului cervical prin vaccinare în The mortality of cervical hpv cancer prevention vaccine in Romania is the most important among European countries. The pri­­ma­­ry cause of cervical cancer is a persistent infection by some spe­ci­­fic types of human papillomavirus HPV. Cer­­vi­cal cancer can be prevented by vaccination against HPV infection and scre­ening. Sincemany countries have introduced HPV vac­cines into their national programs.